"The tandem peptide library used in this work was synthesized via standard FMOC solid-phase peptide synthesis and purified by high-performance liquid chromatography at the MIT Biopolymers Core, Tufts University Core Facility or CPC Scientific, Inc."

Abstract

Aspects of the invention provide compositions and methods for delivering nucleic acids to target cells.

Full Article

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Press Releases, Industry News, Articles, and Technical Content

Characterizing the Effects of the Juxtamembrane Domain on Vascular Endothelial Growth Factor Receptor-2 Enzymatic Activity, Autophosphorylation, and Inhibition by Axitinib.
Solowiej, J., Bergqvist, S., McTigue, M.A., Marrone, T., Quenzer, T., Cobbs, M., Ryan, K., Kania, R.S., Diehl, W. and Murray, B.W. Biochemistry 48, no. 29 (2009): 7019-7031.
- Pfizer Global Research and Development, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, California 92121.
A peptide designed to encompass VEGFR2 residues 786-805 was synthesized and purified to 98% purity (CPC Scientific, San Jose, CA). Compounds were synthesized as described in patents: AG-13736 (35), AG-13974 (36), AG-28038 (35), and AG-28047 (37).

June 15th, 2009Citations
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Memory T cells specific for novel human papillomavirus type 16 (HPV16) E6 epitopes in women whose HPV16 infection has become undetectable.
Wang, Xuelian, et al. Clinical and Vaccine Immunology 15.6 (2008): 937-945.
"A series of 15-mer peptides overlapping each other by 10 amino acids and a series of 9-mer peptides overlapping each other by 8 amino acids covering the HPV16 E6 protein have been described (20). To define the minimal and optimal amino acid sequences of the CD8 T-cell epitope, 8-mer, 10-mer, 11-mer, and homologous peptides (see Table 1) were synthesized as needed (CPC Scientific, Inc., San Jose, CA)."

June 6th, 2008Citations, Peptide Libraries
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Steady-State and Pre-Steady-State Kinetic Evaluation of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CLpro Cysteine Protease: Development of an Ion-Pair Model for Catalysis.
Solowiej, J., Thomson, J.A., Ryan, K., Luo, C., He, M., Lou, J. and Murray, B.W. Biochemistry 47, no. 8 (2008): 2617-2630.
- Pfizer Global Research and DeVelopment, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, California 92121.
Peptide 4 [Dabcyl-KTSAVLQSGFRKME-Edans], peptide 5 [SITSAVLQ-pNA], and peptide 6 [SITSAVLQ-pNP] were purchased from CPC Scientific (San Jose, CA) and had the following purities: >95%, >93%, and >90.1%, respectively.

February 1st, 2008Citations, COVID-19, Dye-Labeled, FRET Substrates
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Quantitative determination of single-bead metal content from a peptide combinatorial library.
Stair, Jacqueline L., et al. Journal of Combinatorial Chemistry 8.6 (2006): 929-934.
"The combinatorial library (CPC Scientific) was composed of the sequence GXXGXXGXXGXX (X = cysteine, aspartic acid, or glutamic acid; G = glycine) and synthesized onto TentaGel Macrobeads..."

October 6th, 2006Citations, Peptide Libraries
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Targeted delivery of nucleic acids.

Ren, Yin, and Sangeeta N. Bhatia. U.S. Patent No. 9,006,415. 14 Apr. 2015.

"The tandem peptide library used in this work was synthesized via standard FMOC solid-phase peptide synthesis and purified by high-performance liquid chromatography at the MIT Biopolymers Core, Tufts University Core Facility or CPC Scientific, Inc."

Abstract

SOCIAL MEDIA

Connect with us and stay updated by following our social media channels.

Latest Briefings from our Knowledge Center

Characterizing the Effects of the Juxtamembrane Domain on Vascular Endothelial Growth Factor Receptor-2 Enzymatic Activity, Autophosphorylation, and Inhibition by Axitinib.

Memory T cells specific for novel human papillomavirus type 16 (HPV16) E6 epitopes in women whose HPV16 infection has become undetectable.

Steady-State and Pre-Steady-State Kinetic Evaluation of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CLpro Cysteine Protease: Development of an Ion-Pair Model for Catalysis.

Quantitative determination of single-bead metal content from a peptide combinatorial library.

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Title

Tel: +1 408-734-3800
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