"The tandem peptide library used in this work was synthesized via standard FMOC solid-phase peptide synthesis and purified by high-performance liquid chromatography at the MIT Biopolymers Core, Tufts University Core Facility or CPC Scientific, Inc."
Abstract
Aspects of the invention provide compositions and methods for delivering nucleic acids to target cells.
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Bhattacharya, Shibani, et al. Biopolymers 97.5 (2012): 253-264.
"The stapled peptides with greater than 90% purity were synthesized by.. CPC Scientific, CA"
December 14th, 2011Citations, Stapled PeptidesKhodai, T., Chappell, D., Christy, C., Cockle, P., Eyles, J., Hammond, D., Gore, K., McCluskie, M.J., Evans, D.M., Lang, S. and Loudon, P.T. Clinical and Vaccine Immunology 18, no. 10 (2011): 1702-1709.
- Vaccines Research Unit, Pfizer Research and Development, Sandwich, United Kingdom
Peptides (CPC Scientific) representing selected sequences of gD and gB that had previously been demonstrated to contain T cell epitopes (data not shown) were synthesized as 15-mers, quality assessed, and formulated into pools representing each protein.
September 1st, 2011CitationsPhillips, Chris, et al. Journal of the American Chemical Society 133.25 (2011): 9696-9699.
"Synthetic peptides that specifically bind nuclear hormone receptors offer an alternative approach to small molecules for the modulation of receptor signaling and subsequent gene expression. [..] Using a number of biophysical techniques, including crystal structure analysis of receptor–stapled peptide complexes, we describe in detail the molecular interactions and demonstrate that all-hydrocarbon staples modulate molecular recognition events."
May 25th, 2011Citations, coauthored, publications, Stapled PeptidesYoung, Travis S., et al. Proceedings of the National Academy of Sciences 108.27 (2011): 11052-11056.
"To determine the IC50 values of the selected cyclic peptides, we chemically synthesized the peptides C2 and G12 in both linear and cyclic forms (CPC Scientific)."
May 23rd, 2011Citations, Peptide MacrocyclesMestecky, Jiri, et al. AIDS Research and Human Retroviruses 27.5 (2011): 469-486.
"The peptides were synthesized as 4-branch MAPS peptides that include a SGGRGG spacer at the C-terminal residue to distance the gp41 sequence from the MAPS (CPC Scientific; San Jose, CA)."
May 4th, 2011Antimicrobial Peptides, CitationsLeone, Marilisa, et al. Chemical Biology & Drug Design 77.1 (2011): 12-19.
"Cyclo-DEYDDPfK; Cyclo-DE(pY)LDPfK; Cyclo-DE(FCOOH)LDPfK (FCOOH= phenylalanine with a carboxyl group at the para position) were purchased either from the MCW facility of the Wisconsin Medical College or from CPC Scientific (San José, CA, USA)"
November 30th, 2010Citations, D-Amino Acids, Peptide Macrocycles, Phosphorylated Peptides, Showcase PhosphorylationPacholec, M., Bleasdale, J.E., Chrunyk, B., Cunningham, D., Flynn, D., Garofalo, R.S., Griffith, D., Griffor, M., Loulakis, P., Pabst, B. and Qiu, X.Journal of Biological Chemistry 285, no. 11 (2010): 8340-8351.
- Departments of Cardiovascular, Metabolic and Endocrine Diseases, and Structural Biology, Pfizer Global Research and Development, Groton, Connecticut 06340
The p53-derived peptides, TAMRA-p53 peptide and native p53 peptide, were custom-synthesized by CPC Scientific.
March 1st, 2010Citations, Dye-LabeledLlenado, R. Alan, et al. Infection and Immunity 77.11 (2009): 5035-5043.
"(R/K)-RMAD-4 [rhesus myeloid α-defensin 4] [(R1/2/5/7/10/13/14/26/33K)-RMAD-462-94] was custom synthesized by CPC Scientific, Inc. (San Jose, CA) and refolded as described previously…"
October 16th, 2009Antimicrobial Peptides, Citations, Multiple Disulfide BridgesCrizer, David M., Yu Xia, and Scott A. McLuckey. Journal of the American Society for Mass Spectrometry 20.9 (2009): 1718-1722.
Phosphopeptide LPISASHpSpSKTR was synthesized by CPC Scientific (San Jose, CA, USA). Both peptides were diluted to a concentration of 20 μM in 49/49/2 (vol/vol/vol) methanol/water/ammonium hydroxide solution."
September 5th, 2009Citations, Phosphorylated Peptides


