"The tandem peptide library used in this work was synthesized via standard FMOC solid-phase peptide synthesis and purified by high-performance liquid chromatography at the MIT Biopolymers Core, Tufts University Core Facility or CPC Scientific, Inc."
Abstract
Aspects of the invention provide compositions and methods for delivering nucleic acids to target cells.
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Bårdsen, Kjetil, Michaela D. Gjerstad, Markku Partinen, Ingeborg Kvivik, Anne Bolette Tjensvoll, Peter Ruoff, Roald Omdal, and Cato Brede. Analytical Chemistry 91, no. 14 (2019): 9323-9329.
Synthetic Hcrt1 with13Cand15N stabile isotopemodification on two leucine amino acids was used for internalstandard (ISTD) calibration; Glp-P-L(U13C6,15N)PDCCR-QKTCSCR-L(U13C6,15N)YELLHGAGNHAAGILTL-NH2(CPC Scientific, Sunnyvale, CA)
June 19th, 2019Citations, Isotope-Labeled PeptidesMcGonigle, Sharon, Utpal Majumder, Donna Kolber-Simonds, Jiayi Wu, Andrew Hart, Thomas Noland, Karen TenDyke et al. Cell Communication and Signaling 17, no. 1 (2019): 67.
Native Cltx (Cltx-CONH2) was synthesized at CPC Scientific (Sunnyvale, CA) by routine methods and stored dry at -20 °C.
June 17th, 2019Citations, Multiple Disulfide BridgesLesniak, W. G.; Mease, R. C.; Chatterjee, S.; Kumar, D.; Lisok, A.; Wharram, B.; Kalagadda, V. R.; Emens, L. A.; Pomper, M. G.; Nimmagadda, S., Molecular Imaging 2019, 18, 1536012119852189.
The PD-L1-binding peptide, WL12 (sequence shown in Figure 1A), was custom synthesized by CPC Scientific (Sunnyvale, California) with >95% purity.
June 12th, 2019Citations, Metal Chelates, Peptide Macrocycles, Showcase Peptide Chelates, Unnatural Amino Acidsto Manufacture Neoantigen Peptides for the PANDA (Personalized and Adaptive) Cancer Vaccine Program.
SUNNYVALE, California, Feb. 19, 2019 – CPC Scientific Inc., a leading global CDMO specializing in synthetic peptide manufacturing, announced today that they will manufacture GMP-grade neoantigen peptides for investigators at UNC Lineberger Comprehesive Cancer Center (LCCC) for the purpose of individualized immunotherapy. CPC […]
February 19th, 2019Press ReleasesMac, Quoc D., Dave V. Mathews, Justin A. Kahla, Claire M. Stoffers, Olivia M. Delmas, Brandon Alexander Holt, Andrew B. Adams, and Gabriel A. Kwong. Nature Biomedical Engineering 3, no. 4 (2019): 281.
"FITC-labelled GzmB substrate peptides with internal quencher ((5-FAM)aIEFDSGK(CPQ2)kkc) were synthesized by CPC Scientific and used for all in vitro activity assays."
February 18th, 2019Citations, D-Amino Acids, Dye-Labeled, FRET SubstratesRohani, Nazanin, Anthony R. Soltis et al. Cancer Research 79, no. 8 (2019): 1952-1966.
100 ul of 40μM Cy7 labled pHLIP peptide (N->C: AC(Cy7)DDQNPWRAYLDLLFPTDTLLLDLLW-DLys-DLys synthesized by CPC Scientific, Inc.)..
February 12th, 2019Citations, Dye-LabeledSasaki, Masako, Ken‐ichi Hamagami et al. Pharmacology Research & Perspectives 7, no. 5 (2019): e00517.
- Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan
The substrates QSY21‐Gly‐Asp‐Asp‐Asp‐Lys‐Ile‐Val‐Gly‐Gly‐Lys(Cy5) and 5FAM‐Abu‐Gly‐Asp‐Asp‐Asp‐Lys‐Ile‐Val‐Gly‐Gly‐Lys(CPQ2)‐Lys‐Lys‐NH2 were purchased from CPC Scientific (Sunnyvale, CA).
February 7th, 2019Citations, Dye-Labeled, FRET SubstratesThis year, “The 7th CPC Symposium on Peptide Therapeutics” will continue the tradition of the successful conferences from previous years. The meeting will offer a forum for scientific discussions of recent developments in the exciting field of peptide therapeutics. It will feature lectures on a broad range of topics including new technologies, drug discovery, CMC, […]
January 25th, 2019Press ReleasesLee, Chul-Jin, Mitra S. Rana, Chanhyung Bae, Yan Li, and Anirban Banerjee. Journal of Biological Chemistry 294, no. 1 (2019): 231-245.
Substrate-mimicking peptides for wild-type or mutant Wnts with a point-mutation, varying in lengths or the number of disulfide bonds were purchased from CPC Scientific (Sunnyvale, CA)..
November 12th, 2018Citations, Multiple Disulfide Bridges


